MetalloClear

Help Clear Heavy Metals with MetalloClear

The World’s Polluted—You Don’t Have to Be!

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Environmental Pollution: A Growing Threat

According to the Environmental Protection Agency and other leading sources, U.S. industry releases over 4 billion pounds of toxic chemicals—including 72 million pounds of recognized carcinogens—into the environment each year.^1,2 This environmental pollution puts your patients at risk for exposure to heavy metals such as:

• cadmium, which is inhaled from polluted air and eaten in food raised in contaminated soil
• lead, which comes from numerous sources, including drinking water, contaminated soil, household dust, and lead-based paint in older homes.

According to the Centers for Disease Control and Prevention (CDC) Third National Report on Human Exposure to Environmental Chemicals, 1.6% of all American children ages 1 year to 5 years have elevated blood lead levels—and about 5% of the population aged 20 and older have high urinary cadmium levels.³

It’s increasingly hard for people to get enough good nutrition to help detoxify these environmental assaults on the body. And over time, accumulating pollutants can reduce energy levels, and negatively impact immune, neurological, and overall health.

MetalloClear: A Clear Difference

Fortunately, you can fight back against our polluted environment with MetalloClear, a revolutionary approach to enhancing heavy metal metabolism. MetalloClear helps patients stay healthy in a toxic environment by providing specialized support to naturally enhance the body’s clearance of specific heavy metals that can negatively impact health and vitality.

Research suggests that metal-binding proteins called metallothioneins (MTs) play an important role in heavy metal detoxification.^4,5 Zinc, in turn, plays a central role in the metal-inducible transcriptional activation of metallothionein and other genes involved in metal homeostasis and cellular stress response.^4,5 MetalloClear is made from a proprietary formula containing zinc (as zinc citrate), Andrographis (Andrographis paniculata), Turmeric (Curcuma Longa), Hops (Humulus lupulus), and Luduxin^®†.

Exciting new research* suggests that MetalloClear’s ingredients:

• Support the clearance of specific heavy metals, but do not facilitate the excretion of certain healthful minerals such as calcium, magnesium, selenium, and zinc
• Have no serious reported adverse effects, unlike some other approaches

* Based on clinical evaluations at the Functional Medicine Research Center^SM—the clinical research arm of Metagenics.

† Luduxin^® consists of reduced-iso-alpha acids (from hops extract, Humulus lupulus) and magnesium salt produced via a proprietary process.

To order MetalloClear click here.

References

1. Scorecard: The Pollution Information Site. Pollution Locator: Toxic Chemical Releases. www.scorecard.org/env-releases/us-map.tcl. Accessed March 19, 2008.
2. Environmental Protection Agency, TRI Explorer. Releases: Chemical Report. http://www.epa.gov/cgi-bin/broker?view=USCH&trilib=TRIQ0&sort=_VIEW_&sort_fmt=1&state=All+states&county=All+counties
   &chemical=All+chemicals&industry=ALL&year=2006&tab_rpt=1&fld=RELLBY&fld=TSFDSP&_service=oiaa
   &_program=xp_tri.sasmacr.tristart.macro. Accessed March 19, 2008.
3. Centers for Disease Control and Prevention, Third National Report on Human Exposure to Environmental Chemicals 2005. http://www.cdc.gov/exposurereport/report.htm. Accessed March 20, 2008.
4. Yongyi B, Palmiter R, Wood K, Qiang M. Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc. Biochem J 2004;380(6):695-703.
5. Saydam N, Adams T, Steiner F, Schaffner W, Freedman J. Regulation of metallothionein transcription by the metal-responsive transcription factor MTF-1. J Biol Chem 2002;277(73):20438-20445

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

©2008 Metagenics, Inc.